Intermediates

Apixaban

API

Apixaban Intermediate 1

Chemical Name:
4, 5, 6, 7-Tetrahydro-1-(4-methoxyphenyl)-7-oxo -6-(4-(2-oxopiperidin-1-yl)phenyl)-1Hpyrazolo 3,4pyridine-3-carboxamide

CAS Number: 503612-47-3

Intermediate

Apixaban Intermediate 1

Chemical Name:
3-Morpholino-1-(4-(2-oxopiperidin-1-yl)phenyl)-5,6-dihydropyridin-2(1H)-one

CAS Number: 545445-44-1

Intermediate

Apixaban Intermediate 2

Chemical Name:
1-(4-methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl) phenyl)-4, 5, 6, 7-tetrahydro-1H-pyrazolo [3, 4-c] pyridine-3-carboxylic acid ethyl ester

CAS Number: 503614-91-3

Intermediate

Apixaban Intermediate 3

Chemical Name:
1-(4-Aminophenyl)-5, 6-dihydro-3-(4-Morpholinyl)-2-(1h)-pyridinone

CAS Number: 127610-26-3

Intermediate

Apixaban Intermediate 4

Chemical Name:
(Z)-Ethyl 2-chloro-2-(2-(4-methoxyphenyl)hydrazono)acetate

CAS Number: 27143-07-3

Dapagliflozin

API

Dapagliflozin API

Chemical Name:
(1S)-1,5-Anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-D-glucitol

CAS Number: 461432-26-8

Intermediate

Dapagliflozin Intermediate 1

Chemical Name:
4-Bromo-1-chloro-2-(4-ethoxybenzyl)benzene

CAS Number: 461432-23-5

Intermediate

Dapagliflozin Intermediate 2

Chemical Name:
(2R,3R,4R,5S,6S)-2-(Acetoxymethyl)-6-(4-chloro-3-(4-ethoxybenzyl)phenyl) tetrahydro-2H-pyran-3,4,5-triyl triacetate

CAS Number: 461432-25-7

Intermediate

Dapagliflozin Intermediate 3

Chemical Name:
2,3,4,6-Tetrakis-O-trimethylsilyl-D-gluconolactone

CAS Number: 32384-65-9

Rivaroxaban

API

Rivaroxaban API

Chemical Name:
5-Chloro-N-({(5S)-2-oxo-3-[4-(3-oxo-4-morpholinyl)phenyl]-1,3-oxazolidin-5-yl}methyl)- 2-thiophene-carboxamide

CAS Number: 366789-02-8

Intermediate

Rivaroxaban Intermediate 1

Chemical Name:
4-[4-[[(2R)-3-Chloro-2-hydroxypropyl]amino]phenyl]-3-morpholinone

CAS Number: 1252018-10-2

Intermediate

Rivaroxaban Intermediate 2

Chemical Name:
(2R)-2-Hydroxy-3-[4-(3-oxo-4-morpholinyl)phenyl]-1H-isoindole-1,3(2H)-dione

CAS Number: 446292-07-5

Intermediate

Rivaroxaban Intermediate 3

Chemical Name:
2-({(5S)-2-oxo-3-[4-(3-oxo-4-morpholinyl)phenyl]-1,3-oxazolidin-5-yl}methyl)- 1H-isoindole-1,3(2H)-dione

CAS Number: 446292-08-6

Intermediate (HCl)

Rivaroxaban Intermediate HCl

Chemical Name:
(5S)-4-{4-[5-(Aminomethyl)-2-oxo-1,3-oxazolidin-3-yl]phenyl} morpholine-3-one Hydrochloride

CAS Number: 898543-06-1

Sitagliptin

API

Sitagliptin API

Chemical Name:
(3R)-3-Amino-1-[3-(trifluoromethyl)-5,6,7,8-tetrahydro-1,2,4-triazolo [4,3-a]pyrazin-7-yl]-4-(2,4,5-trifluorophenyl)butan-1-one Phosphate Hydrate

CAS Number: 654671-77-9

Intermediate

Sitagliptin Intermediate 1

Chemical Name:
1-(3-(Trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)- 4-(2,4,5-trifluorophenyl)butane-1,3-dione

CAS Number: 764667-65-4

Intermediate

Sitagliptin Intermediate 2

Chemical Name:
3-(Trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine hydrochloride

CAS Number: 762240-92-6

Intermediate

Sitagliptin Intermediate 3

Chemical Name:
2,2-Dimethyl-1,3-dioxane-4,6-dione

CAS Number: 2033-24-1

Teneligliptin HBr

API

Teneligliptin API

Chemical Name:
[(2S,4S)-4-[4-(3-methyl-1-phenyl-1H-pyrazol-5-yl)-1-piperazinyl] -2-pyrrolidinyl]-3-thiazolidinyl-methanone, hydrobromide hydrate

CAS Number: 1572583-29-9

Intermediate

Teneligliptin Intermediate

Chemical Name:
4-[4-(5-Methyl-2-phenyl-2H-pyrazol-3-yl)-piperazin-1-yl]- 2-(thiazolidine-3-carbonyl)-pyrrolidine-1-carboxylic acid tert-butyl ester

CAS Number: 401566-80-1

Ticagrelor

API

Ticagrelor API

Chemical Name:
(1S,2S,3R,5S)-3-[7-[[(1R,2S)-2-(3,4-Difluorophenyl)cyclopropyl]amino]- 5-(propylsulfanyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl]- 5-(2-hydroxyethoxy)cyclopentane-1,2-diol

CAS Number: 274693-27-5

Intermediate

Ticagrelor Intermediate 1

Chemical Name:
2-[[(3aS,4R,6S,6aS)-4-[7-[[(1R,2S)-2-(3,4-Difluorophenyl)cyclopropyl]amino]- 5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl]- 2,2-dimethyltetrahydro-3aH-cyclopenta[d][1,3]dioxol-6-yl]oxy]ethanol

CAS Number: 274693-26-4

Intermediate

Ticagrelor Intermediate 2

Chemical Name:
2-[6-(5-Amino-6-chloro-2-propylsulfanyl-pyrimidin-4-ylamino)- 2,2-dimethyltetrahydro-cyclopenta[1,3]dioxol-4-yloxy]-ethanol

CAS Number: 376608-74-1

Intermediate

Ticagrelor Intermediate 3

Chemical Name:
4,6-Dichloro-2-propylsulfanyl-pyrimidin-5-ylamine

CAS Number: 145783-15-9

Intermediate

Ticagrelor Intermediate 4

Chemical Name:
2-((3aR,4S,6R,6aS)-6-Amino-2,2-dimethyltetrahydro-3aH- cyclopenta[d][1,3]dioxol-4-yloxy)ethanol L-tartaric acid

CAS Number: 376608-65-0

Valsartan

API

Valsartan API

Chemical Name:
(S)-3-methyl-2-(N-{[2'-(2H-1,2,3,4-tetrazol-5-yl)biphenyl-4-yl]methyl} pentanamido)butanoic acid

CAS Number: 137862-53-4

Intermediate

Valsartan Intermediate 1

Chemical Name:
Valsartan Barium salt

CAS Number: —

Intermediate

Valsartan Intermediate 2

Chemical Name:
N-{[2’-cyanobiphenyl-4-yl)methyl]}-(L)-valine methyl ester Hydrochloride

CAS Number: 137862-53-4

Vildagliptin

API

Vildagliptin API

Chemical Name:
(S)-1-[2-(3-Hydroxyadamantan-1-ylamino)acetyl] pyrrolidine-2-carbonitrile

CAS Number: 274901-16-5

Intermediate

Vildagliptin Intermediate 1

Chemical Name:
2(S)-1-Chloroacetyl-pyrrolidine-2-carbonitrile

CAS Number: 207557-35-5

Telmisartan

API

Telmisartan API

Chemical Name:
4′-[(1,4′-dimethyl-2-propyl-2,6′-bi-1H-benzimidazol-1′-yl) methyl]-[1,1′-biphenyl]-2-carboxylic acid

CAS Number: 144701-48-4

Intermediate

Telmisartan Intermediate

Chemical Name:
4-(Bromomethyl)-2-cyanobiphenyl

CAS Number: 114772-54-2

Amlodipine Besylate

API

Amlodipine Besylate API

Chemical Name:
3-ethyl 5-methyl 2-[(2-aminoethoxy) methyl]-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate benzenesulfonate

CAS Number: 111470-99-6

API

S-Amlodipine Besylate API

Chemical Name:
(S)-3-ethyl 5-methyl 2-[(2-aminoethoxy) methyl]-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate benzenesulfonate

CAS Number: 884648-62-8

Intermediate

Amlodipine Intermediate 1

Chemical Name:
N-(2-hydroxyethyl) Phthalimide

CAS Number: 3891-07-4

Intermediate

Amlodipine Intermediate 2

Chemical Name:
Ethyl 4-[(1,3-dioxoisoindolin-2-yl)butoxy]-4-oxobutanoate

CAS Number: 22952-24-5

Intermediate

Amlodipine Intermediate 3

Chemical Name:
Methyl (E)-3-aminobut-2-enoate

CAS Number: 3014-72-2

Intermediate

Amlodipine Intermediate 4

Chemical Name:
3-Ethyl 5-methyl 2-[(2-aminoethoxy) methyl]-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate

CAS Number: 88150-62-3

Intermediate

Amlodipine Intermediate 5

Chemical Name:
3-ethyl 5-methyl 2-[(2-aminoethoxy) methyl]-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate

CAS Number: 88150-42-9

Intermediate

S-Amlodipine Intermediate

Chemical Name:
(S)-3-ethyl 5-methyl 2-[(2-aminoethoxy) methyl]-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate

CAS Number: 103129-82-4

Diloxanide Furoate

API

Diloxanide Furoate API

Chemical Name:
4-[(2,2-dichloro-N-methylacetamido)] phenyl furan-2-carboxylate

CAS Number: 3736-81-0

Intermediate

Diloxanide Intermediate 1

Chemical Name:
p-methyl aminophenol sulfate

CAS Number: 55-55-0

Intermediate

Diloxanide Intermediate 2

Chemical Name:
2,2-Dichloro-N-(4-hydroxyphenyl)-N-methylacetamide

CAS Number: 579-38-4

Intermediate

Diloxanide Intermediate 3

Chemical Name:
Furan-2-carboxylic acid

CAS Number: 88-14-2

Losartan Potassium

API

Losartan Potassium API

Chemical Name:
Potassium 2-butyl-4-chloro-1-[(2′-(1H-tetrazol-5-yl) biphenyl-4-yl) methyl]-1H-imidazole-5-methanol

CAS Number: 124750-99-8

Intermediate

Losartan Intermediate 1

Chemical Name:
2-Butyl-4-chloro-1-[(2′-cyanobiphenyl-4-yl) methyl]-1H-imidazole-5-methanol

CAS Number: 114772-55-3

Intermediate

Losartan Intermediate 2

Chemical Name:
2-Butyl-4-chloro-1-[(2′-(1H-tetrazol-5-yl) biphenyl-4-yl) methyl]-1H-imidazole-5-methanol

CAS Number: 2904682-23-9

Norfloxacin

API

Norfloxacin API

Chemical Name:
1-Ethyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid

CAS Number: 70458-96-7

Intermediate

Norfloxacin Intermediate 1

Chemical Name:
Ethyl 7-chloro-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylate

CAS Number: 75073-15-3

Intermediate

Norfloxacin Intermediate 2

Chemical Name:
7-chloro-6-fluoro-1-ethyl-4-oxo-1,4-dihydroquinoline-3-carboxylic acid

CAS Number: 68077-26-9

Pefloxacin Mesylate

API

Pefloxacin Mesylate API

Chemical Name:
1-Ethyl-6-fluoro-7-(4-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid methanesulfonate

CAS Number: 70458-95-6

Intermediate

Pefloxacin Intermediate

Chemical Name:
1-Ethyl-6-fluoro-7-(4-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid

CAS Number: 70458-92-3